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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e03af981789d3061d1a84633b17b152cb0c59a72d2963846e4fab8a5976adad' 
  AND token = 'I5k/LPX5tV/MfMntjefn4yJTosok3xIonF3cw+pKyi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}