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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '455651286eedb3cae1cbe1561d40d0716c763cd72f442c03389c659259fc2539' 
  AND token = 'AViBcqrv1RCiO47ver4RQJ5coyXjP2LfiBuZKBkq2V8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}