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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1537a82e0c2a7eb175a7cddd625d7d86df390772eab3bd0c959b4816e8c008c1' 
  AND token = 'vtKskKMJCzz1NnjSY7lmp5kDupZOlnIY/y0hjB1sQlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}