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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd287594ca1821b0fd2d5784868d69f8c2543460f320c0ff6b2219575fd1182a' 
  AND token = 'y65diu1fnvTmoloyjoA5oY58l6bnUpfPy4kr37uPhtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}