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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1788f4bdd6a6908e6f56742c55451417c09ac4f1b73149b8fcf48a6481e25e62' 
  AND token = 'nEjwyLMSMuaW1DLsb7AYGNvOH9W0MOFM9sqHKw0N3f8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}