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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e1b3e307d6c8c6c6f25902ec96a3efb8bd4cdaea1c47305a830f607ca3b7bfc' 
  AND token = 'MycWmehZbqRC6rf+ctscRwNlaMoWP4Gk5kkKZse85l8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}