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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '738e154069ddd04adf67ac601772b1d3be386a15fe328204dc4f18f168da99cc' 
  AND token = '2Q/Kpr8aFsLGDYjvzLbQySaUK5kXxSn757vyGAL/iu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}