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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462cccbfb0f3264b8253e27f00343da1beaf4e85c8d7d655d1825250fdaabf05' 
  AND token = '/LjOAawNvKd4nRrEW04i7i+r63lBaUIV8IpyewORp40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}