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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e8dfeed1a01136e7a9d892e7329cdbc0fb130b5cd7c92b03dd0b333416d916f' 
  AND token = 'xxeY4IdXIjULix3sWmYt7rNmR2xR8SpgQOgZNdIC/tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}