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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf04902dd8f0dc9faac515c1b57d7967f269077a8492dc8006a27d0382c8cec' 
  AND token = '/mwQnRNgGVUx1F0xwzun6zLd3D86lXbzCM8AAEksVHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}