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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357b229fef388069429431714c0da29619786687c5ac9cbb3c16054e7710feb0' 
  AND token = 'gBG+SMYA+pwAoN10SVz2kqWsk83bi4HiSAiQUuymG3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}