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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc3b67bcc9b76c52c271ea46d0f5690ac6afba43eaae2222174d8cdb61a5f582' 
  AND token = '45CZMWvN/bFBylkWQUgR1CFRD9CvWmccbQ24kLmZHyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}