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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f2052f852abca85fe2bc5b8f35a52c72c49b613f96a865fe2273fcdfc3a1575' 
  AND token = 'nUKkfka/NvB66+64vS+sRjfbfQzBKLzjFRJzE1RJLHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}