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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c9f9d8b62efbec9841f7b3e3ac5906792d892060bacad11c4828da1b705f5f' 
  AND token = 'tRq9Mu+7D3O1WbVAGhLX74mesGAmHOAwGFNRzw6+gSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}