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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888a63317b520b1b2828df41a6148447a7c2f78d3baff7e5bd09ba08a157a111' 
  AND token = 'oCxlSBeg43tcgPVHqSa0PnKShIxdz8b66pWkHKL68ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}