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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fda2181f4a4146a628228238facc6428792d00d40485379da93c1a5f59e1770' 
  AND token = 'y/e8xJ0nPHaCRSM9Hz2s/gysdnmx6B4qcyD/pA2o4A0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}