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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e14728b885f848bda25de7a16454eaa1e4c3f84a0be7eaecfb57e75444092a29' 
  AND token = 'YeNr1bMicn521jR9dZM8Vn65I1XlAg+rSX+gDH3v/RM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}