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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42a0b219d771bab393d33964b503d5ae2dbba2bbc1abadbe1e7065b5827040e6' 
  AND token = 'OjnChg428qWgQvk3GLVXDyrlzeq2+rYwtLCBQDAzxuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}