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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a5797fbf42b902ce2e91f8bfc7c575e11a5070ea98fd6c68cecb01529d25ff' 
  AND token = '+I9Iug95skgyw9zIJPHrPqDPBxuE+U56pC0Amgih6ME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}