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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '667c7580286ba806b8553b2fbc5097819979663f48562c65fa7abc50368d5e95' 
  AND token = 'MkFDRthJu7+sv7n972/OFaOhTi5Z/K4Lc3wTuv8Dhqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}