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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168ede9f81164abdb8db446dcce2f81e36b5fb95fc40e4bf05ee37e34116b3a0' 
  AND token = 'CjneUtdqpOylX4Bt52JfUu5NUqxmk9DIzg/m1tldrsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}