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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4daa280182aa6151eb84d2e271d323b751b9000a9e9f6c5eb52218f1c4dc1738' 
  AND token = '9tKWMnq9Q1Et8UV5DQxsURbGIKLCq2kk5n2lXpUyJUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}