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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bc64a19e5f06fe31b34e90b364bf06d2dba385a5d6e1debe9f2b9f809f2204a' 
  AND token = 'T3SsOG2o6h7YyNwjj4LEynwOgbQoG0x0Np7ntDXnBnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}