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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e57954acafb21ab5716900901fa7a6e2de7229535b7eafe04b70675b9fb49736' 
  AND token = '0UKQ+Cje2CfTUheUum6qgOON982cLAISaNa5AqDm7YE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}