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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '020335b99a3558c548d1a4014c10357028ac2ece43ec9c14b3ca0581c3925481' 
  AND token = 'dVc+RrsQPd3QhS+tT8FansMBiyJMRUbDdhyChElQ0Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}