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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36f3cdf28273830e7297fd706fc6bf4f20f50125e261f2bbaa009cea7fcc65e3' 
  AND token = 'fYr4+ivmYnyO8fbTF238yquNN4FqxW32PO7PRjKy4wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}