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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ace270c23eb2e5d614ff832e4a81daa69f0efc858e7149b7805e8fcfc7d3e71e' 
  AND token = 'QA279DtrTYUYKNY0cWd8g53rjA2vqIeqcAAhC8IXvTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}