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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ea0896fa3b96d91cea1d7397edce390d81a71cde9af68c7b577a0bf87a8587' 
  AND token = 's/atd6Fd7j3T/lUd72U5jOCLzrYjw91iPOr55xVYmuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}