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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bff62953a9933cfa6d6b10663da7af2995b15b28bd6e8074a4b9a06821ff350' 
  AND token = 'xPLD0xVSW/gqhrIydOBiaGszAFvGb5rTREcGfXF1vcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}