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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad0e61e56c719f0d0071f909e49003bdeaeadb1b06cb50ba7b9bcff66f615e35' 
  AND token = 'UY+RiZmN3b2jtPrw2fG+S7M//IuiuC7LScA9NvXPpq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}