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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6455ea9c2951fa2d8867d97dfbc1beca3a9be5774e97ebcc6bcac98304b891fa' 
  AND token = 'ddJRY8Xp31O8K3aFXg3odSwGzkpCsfOW87/EF0n5LnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}