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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acc2baa8ef65cf4719ed619d12acd98f302214f44bb66430a1f14dea03af3a7c' 
  AND token = 'LCf/Dy+AZU77G5y8wvs07EoALOm2hf8ZvGsUUUwfi2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}