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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21747fdfaa8e067fdb7367ab0a5b872f7af08bfb880114331d6c21187a1c0e7a' 
  AND token = 'Gss1/76TyT8HNnSsgnVdOsohDZ8U+qg1lUS0FCtGQ9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}