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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6649cf2ad01ab079690ec05289ea8f5ae9a37e79e60c5b992b3845d9f74f7673' 
  AND token = 'hIb2VOBIzYUOyLb9t8YNtk09iBeJV4ga4ZfRhj1hfa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}