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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5195736bf6b5356633105e226290c2a269b5d6ac2a7ea7e6dae9561bb4040f9' 
  AND token = 'aQ9zHXMKEZ8b+hlSR3Ac+2K2Jipcn3RD6T2vm7HEv68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}