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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3eb2b6e34f53a3a5e8f0b08c667b9ebd3abf1f46d9a49cd60565e6dc733ebb6' 
  AND token = 'TPGS9tpo2qUWtvxJSyCmAudxOg3mx+4VOaDw2dJTRXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}