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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dd8738858c1f83721f21a3a30ea015e1ddeddf85c8058530ab0af3b07b0abed' 
  AND token = '6DtIVedNTaeDFzptgkgg2vhI1ooaE6PaFvr1Mf9ZeSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}