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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e0f9f438fc29fcea4d191e4a05c96f1ee77dca35a7da5a1018346e1027e2536' 
  AND token = 'dP8yWqoglD7AaeGJvDHZBwnE801mpRoGri9bOUGFTEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}