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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e20abc6c98db5023e09d16c5cbd64ef23ce50be8bd572db7d23a3f8697e5d759' 
  AND token = '2kUTumaSRWFNllGWzVSK7qV7a6xCVRz3fLxWIxJUHuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}