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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a92107a06c0bec1093a18c86512ce8ea42101d3803df29f119d3dcda1af0c5' 
  AND token = '2sRI/p2/YORoH8E9hzv6F8v35/gLaGDHRqGD9Js5jRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}