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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4215ddca35fcb1d6b3fa104ebe1129f4be8ce0a75429085712e7797c5419edd9' 
  AND token = 'oM5YP1xbxmqKe1W25GnGHCLwtgyIHKTeeFk0Ud4a/1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}