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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72c30edace09a6740c02a0c6e5cb9b1a457e886f4878dfa202364a49bfffb7fa' 
  AND token = 'NMuOSe/5Wvn4xGtymg6mFv00sE8nrOmrJdm5aKIx8QA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}