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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b9ed1dee307a9164221b502ee2f8ec412bae7253fe9c095a5dfe7d1af9fe00a' 
  AND token = '9/2H6AGBkuBC+U2WT1+OnGqpN9Xi6k0VfktotbgvZOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}