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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf218e4584d01c0b98d3c0cca32b946c0a65f6f8343c3631d59db7984b5d3ac8' 
  AND token = 'Y6j/p3NHKsMHxOsEPSXFtLGSeBoPKkoq5owarPqJuLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}