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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e2639e0e116902d74707a82692c964446e70f53052cdf862143042c06139a8f' 
  AND token = 'TMxxoUvQZ1tZbP/Ib0/ER78rF2Vr6VU6fUakLOu+UmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}