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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '005280125e145d887608b9c38be5c84f09bb3a6308e9d6cffd772d1d7b88f7fc' 
  AND token = 'ElO6SeSbdWh8SVCYuJfr93PhTlHQJcwiSJSF8vfgtws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}