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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8829971a9d9560b889d3f6fc20bcb71aca06b01a725f2c699b62b2302662222' 
  AND token = 'D3W1vbYhyrHyoa5c6WaODqIgHgidJ39lzpenaubdFUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}