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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f91777e53f0992801c2c552d0ade61d0b755c8bbed3edf0dc741485fb9b778' 
  AND token = 'gnTx2uZZWM0avG1M2g+7OEyvJruAaNFbApLHwrpPh4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}