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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39095ca8bff84f1b64ac991cdaf381dbdd84bd879b2d894bc27913781e4a6df9' 
  AND token = 'VUehMfot1/a+6zY5pgh5W1oft9HBamKu0yAGCU7rX88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}