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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dcdbd8d5f97aa4d99661783c081b889044a90a0764ef4913ee571450cbfce65' 
  AND token = 'vBMgGSMNjDGR6ml15vmBEaGvk4IrjR4ZqubtJ5LyjRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}